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IV delivery puts the vitamin directly into the blood

Animal studies show minimal toxicity at therapeutic doses over 11 days, with no observed hepatotoxicity, nephrotoxicity, or CNS effects

Getting enough vitamin D helps keep bones strong and may help prevent osteoporosis

N Engl J Med

While semaglutide does not require dose adjustment for mild to moderate renal impairment, experience in patients with severe renal impairment is limited