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Corresponding authors of publications were contacted for missing data

Figure 2 illustrates the schematic pathway from protein production to purification with the studied solubility tags (His 6 tag, GST, MBP, NusA, Trx, SUMO, H, and Fh8)

Advances in diagnostic strategies, including quantitative imaging modalities and circulating biomarkers, alongside ongoing progress toward laboratory determinants and assay standardization, have begun to refine disease characterization and translational potential, though consensus remains limited

Similarly, the affinity of cystathionine for CSE is greater than that of cysteine, favouring the generation of cysteine as opposed to H 2 S