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These estimates echo those reported in larger clinical implementation trials such as the PREPARE study, which demonstrated reduced ADR rates when pharmacogenetic guidance informed prescribing decisions (Swen et al., 2023)

Nina Dickerhof, University of Otago, Christchurch, New Zealand Updates Copyright 2023 Eben and Imlay

Nat Rev Nephrol 12:325338 Aminzadeh MA, Nicholas SB, Norris KC, Vaziri ND (2013) Role of impaired Nrf2 activation in the pathogenesis of oxidative stress and inflammation in chronic tubulo-interstitial nephropathy

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