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Survival analysis was done with the Kaplan-Meier survival curve

Vitamin B12 encourages cell renewal, helping to replace damaged or dead skin cells with fresh, healthy ones

Epigenetic regulation of macrophage polarization and function

Additionally, while ceramides promote apoptosis by BAX dependent mechanisms, sphingolipid metabolism co-operates with BAK/BAX dependent mechanisms to promote permeabilization of the mitochondrial outer membrane (MOMP) (135, 136)