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10.1093/humupd/4.1.3

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doi:10.1371/journal.pone.0206224 1045. Mazarico-Altisent I, Capel I, Baena N, Bella-Cueto MR, Barcons S, Guirao X, Albert L, Cano A, Pareja R, Caixs A, et al

Several bacterial taxa can also affect tryptophan levels by direct utilization for growth or via tryptophanase expression (28, 203, 204), and these bacteria have been associated with the development of neuropsychiatric disorders, including autism spectrum disorders (205)

The respiratory region, densely populated with blood capillaries, facilitates systemic drug absorption and subsequent indirect drug transport to the IN route (61)