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Their structural similarity (both seven-amino-acid stabilized fragments) is part of why they're often grouped together, but their research applications are genuinely distinct

Regarding the descriptive resolution, almost all molecular techniques including 16S rRNA and metagenome sequencing for studying microbial communities can only identify the species level but not the strain level (Prosser 2020)

Girgenti MJ, Wang J, Ji D et al (2021) Transcriptomic organization of the human brain in post-traumatic stress disorder

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Latvia Research suggests that senescent cells impair proteasome activity in the heart, leading to the accumulation of damaged proteins and reduced cardiac function