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Limitations and realistic expectations

Growing evidence suggests that targeting ferroptosis may offer benefits for CNS disorders, driving the development of effective inhibitors (24,95)

In the absence of Cur-AuNPs, no oxidation of TMB was observed, even in the presence of HO, indicating that the reaction is not spontaneous and confirming the necessity of a catalyst, similar to the action mechanism of horseradish peroxidase (HRP)

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To establish a mouse model of hypercholesterolemia-induced atherosclerosis, we fed 8-week-old male LDLR / mice D12108 feed containing 1.25% cholesterol for 8 weeks