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This article covers the biological mechanisms BPC-157 targets in reflux pathology, the preclinical evidence base for gastric mucosal protection, the absence of human clinical trials, and what researchers should understand about peptide purity and storage when designing GERD-related studies

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This group has also recently reported (2025) that intravenous administration of BPC 157 had no side-effects and was well-tolerated in two women

It is advisable to measure PCT in the initial evaluation phase, in the same way as C-reactive protein or leukocytes are measured in the context of inflammatory response evaluation