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Loss of Grx1, either by oxidative stress or genetic silencing, increases eNOS glutathionylation and further NO synthesis (Chen et al., 2013)

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belongs to the Zingiberaceae family, is indigenous to South Asias tropical areas

In addition, patients with tophi are often at risk for uric acid-related kidney stones, since they may be over-producers of uric acid and have elevated 24-hour urinary uric acid