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When activated, the Nrf2 pathway upregulates the expression of a wide range of genes that help to protect cells against various stressors such as reactive oxygen species (ROS), electrophiles, and xenobiotics

A human clinical study published in PLOS ONE found that oral supplementation with L

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However, we found low heterogeneity between the five trials in all-cause mortality (I 2 = 22%) (Figure 2) and detected no heterogeneity between the two trials reporting heart failure (I 2 = 0%), unstable angina (I 2 = 0%), and myocardial reinfarction (I 2 = 0%) (Figure 3)