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Eur J Endocrinol (2000) 142:50611

Increased levels of saturated fatty acids (FFA) and glucose in the blood are considered to be major mediators of signals that bind -cells to apoptosis and death for T2 DM

The deltoid (upper arm) is also an IM site but can be harder to reach on your own

From the head of the bed, I see the same pattern you're describing at the tissue level - just earlier in the arc

While overall urinary GSH levels before and after the treatment did not show a significant difference (Supplemental Figure 16A), a significant decrease in urinary GSH levels was observed in seven patients who experienced more than a 50% reduction in urinary protein levels after steroid treatment (Supplemental Figure 16B)