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Ovarian primordial follicular cells cannot regenerate, and aberrant death of these cells by chemotherapeutics leads to follicular dysfunction and oocyte atresia, which appears as POI 54

Moors TE, Maat CA, Niedieker D, Mona D, Petersen D, Timmermans-Huisman E, Kole J, El-Mashtoly SF, Spycher L, Zago W, Barbour R, Mundigl O, Kaluza K, Huber S, Hug MN, Kremer T, Ritter M, Dziadek S, Geurts JJG, Gerwert K, Britschgi M, van de Berg WDJ (2021) The subcellular arrangement of alpha-synuclein proteoforms in the Parkinsons disease brain as revealed by multicolor STED microscopy

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[10] Your doctor may prescribe antibiotics or pain relievers depending on what they find during your appointment