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Because the signal goes through the body's own pituitary, GH is released in pulses rather than as a constant synthetic level the appeal over direct GH injection

BAs act in the brain by interacting with key receptors on neurons and glial cells-Farnesoid X receptor (FXR), Takeda G protein receptor 5 (TGR5), GR, and sphingosine-1-phosphate receptor 2 (S1PR2

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