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Notably, cGAS- and BAX-dependent microglial senescence was exacerbated by the combined presence of the APOE4 allele and the TREM2 R47H variant, indicating both associated with increased risk and earlier onset of Alzheimer's disease and their potential role as upstream modulators of AD pathogenesis (Carling et al., 2024)

When symptoms persist or tear severity increases, surgeons perform arthroscopic procedures to trim damaged cartilage or repair the torn meniscus with sutures

Microglial surveillance and response mechanisms in the healthy and damaged brain In healthy brains, microglia continuously sense the alterations in CNS microenvironment by extending and retracting their processes

Mar 29 2023;12(7)doi:10.3390/jcm12072591

Hasina is currently living in exile in Indias capital, New Delhi, but is expected to return to Bangladesh in December, according to the Reuters news agency, which reported news of Shahabuddins expected resignation on Thursday