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This dysregulation of CAT and subsequent ROS accumulation contribute to vascular injury, which in turn plays a pivotal role in the development of carotid plaque formation and bleeding, thereby contributing to the progression of AS [130]

The Glucagon-Like Peptide-1 Receptor Agonist Exendin-4 Inhibits Lipopolysaccharide-Induced Osteoclast Formation and Bone Resorption via Inhibition of TNF-alpha Expression in Macrophages

10.1016/j.scitotenv.2014.12.064 32 CherkasovA

Based on these findings, the possible mechanisms of action of AGE on the process of neuroinflammation in A-induced AD have been proposed (51)

The tissues were homogenized (in a pool of 2 organisms) to 5% w/v in a Tris-HCl buffer in pH 7.6 in Tris-HCl buffer (50 mM Tris