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J Clin Invest 112:17961808

[DOI] [PMC free article] [PubMed] [Google Scholar] 83.Wu S.Y

Anti-inflammatory signalling (preclinical): KPV has shown anti-inflammatory activity via NF-B in cell studies [11]

Chemical synthesis of human proteoforms and application in biomedicine

Thus, VEGFAinduced pathways and NLRP3 inflammasome components may serve as novel therapeutic targets to inhibit these major common aging diseases of the eye without impairing the adult microvasculature, as would be expected to occur when targeting VEGFA continuously