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Gefitinib inhibited the downregulation of ER by EGFR and restored the sensitivity of cells to tamoxifen to a certain extent (Jeong et al., 2019)

Scaling up

Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter

Myofibroblasts, the key effector cells in fibrosis, arise from fibroblasts, pericytes, endothelial cells, or epithelial cells via epithelialmesenchymal transition (EMT) under stimulation by transforming growth factor (TGF) -, clotting factors, and mechanical stress [11, 29, 34, 36]

Foods high in vitamin A include: Dairy products Eggs Fortified cereals Fruits like cantaloupe and pumpkin Vegetables like spinach, broccoli, carrots, and sweet potatoes 3