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Interestingly, neurogenesis is closely associated with pro-inflammatory cytokines and neuroinflammation

Such modified proteins are known to initiate an autoimmune response and has been considered to be responsible for the initiation and progression of several disease processes

On the other hand, targeted drugs may require less time and cost in the initial stage of development but could necessitate more late-stage investment to address resistance and side effects

419 LLPS LLPS is a novel mechanism for the generation of cell compartments and condensates, known as membraneless organelles (MLOs)

In honor of patient#1, the investigators named this novel ACOX1-mediated disease Mitchell Syndrome (distinct from Mitchell's disease, Erythromelalgia)