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Description

Culture of isolated adult neurons was as previously described [19]

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Oral Bioavailability and Metabolic Stability Many bioactive constituents derived from TCM, particularly glycosides (eg, paeoniflorin, forsythoside A) and alkaloids (eg, berberine), exhibit poor oral bioavailability attributable to limited gastrointestinal stability, efflux transporter involvement, and extensive Phase II metabolism including glucuronidation and sulfation

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doi: 10.3389/fnmol.2018.00486 187 ZhuRZengSLiNFuNWangYMiaoMet al

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