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10.1371/journal.pone.0146797 Summary Keywords autism, folinic Acid, glutathione, methylation, methylcobalamin, oxidative stress, tetrahydrobiopterin Citation Delhey LM, Tippett M, Rose S, Bennuri SC, Slattery JC, Melnyk S, James SJ and Frye RE (2018) Comparison of Treatment for Metabolic Disorders Associated with Autism:Reanalysis of Three Clinical Trials

doi: 10.1186/s40364-017-0081-z [DOI] [PMC free article] [PubMed] [Google Scholar] 76

These increases activated NRF2 and its downstream target HO-1 in a dose-dependent manner to attenuate the inflammation caused by IH in the pulmonary tissue (Wang et al