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Liver tumors frequently exhibit overexpression of one or more proteins belonging to the antioxidant system, for example, glutathione reductase (GSR), glutathione S-transferase P (GSTP), gamma-glutamyl transferase (GGT), glucose-6-phosphate dehydrogenase (G6PD), thioredoxin reductase (TXNR), NAD(P)H dehydrogenase [quinone] 1 (NQO1), and prostaglandin reductase 1 (PTGR1)