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What remains poorly studied though, is which sources of histamine within the CNS may contribute to both microglia-mediated neuroinflammation and altered neurodevelopment

and (4) are there any adverse or toxic effects under various dosing schedules

Brain 127:19281941 Storch M, Stefferl A, Brehm U, Weissert R, Wallstrom E, Kerschensteiner M, Olsson T, Linington C, Lassmann H (1998) Autoimmunity to myelin oligodendrocyte glycoprotein in rats mimics the spectrum of multiple sclerosis pathology

Gross S, Tilly P, Hentsch D, Vonesch J-L, Fabre J-E

HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3