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Despite the growing evidences of the importance of S-palmitoylation and the attractive therapeutic perspectives that it provides, the full extent of the S-palmitoylated proteomes is not well defined and our understanding of the mechanisms that regulates S-palmitoylation and its consequences on cellular and organismal levels function remains incomplete

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5A, the footprints of the NC group (red) were straight, whereas the footprints of the ROT group (orange) were irregular, indicating an unstable motor function

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