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N -(5-(((5-( tert -butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)-1-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)thio)acetyl)piperidine-4-carboxamide ( 7 )

2.15 Statistics Statistical significance was determined using a two-sided Welchs t test

The depletion of ER Ca 2+ promotes the formation of mitochondrial-associated ER membrane, leading to mitochondrial Ca 2+ overload and dysfunction

In these studies, the dietary habits of omnivorous mammals closely resembled those of humans consuming mixed diets, whereas herbivorous feeding patterns showed similarities to plant-based dietary regimens in humans (67)