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Severe multisystem symptoms require specialist evaluation Seizures, metabolic strokes, severe weakness, cardiomyopathy, developmental regression, exercise-induced rhabdomyolysis, lactic acidosis, major hearing or vision loss and strong maternal inheritance patterns may require neurological, metabolic or genetic evaluation

Future investigations warrant substantially larger sample sizes to increase power to detect potentially clinically relevant differences, especially in pediatric subjects

doi: 10.1002/hep.30652 63 GuCZhouZYuZHeMHeLLuoZet al

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This s-acetyl glutathione supplement form is well-absorbed and more stable throughout the digestive tract than other forms on the market.*