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COPD patients with co-morbidities like rheumatoid arthritis or cognitive disorders, who may be exhibiting a lack of ability to operate other handheld inhaler devices effectively

This provides the scientific community with the foundation to propose possible mechanisms of pathogenesis and develop treatment modalities to limit morbidity and mortality

A rate of increase of 1 fluorescence unit per minute on the recorder was calibrated to correspond to a rate of formation of conjugate of 0.1 nmoles ml -1 min -1

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