glutathione inhibits melanin production works for skin by reducing production, which helps lighten the skin and reduce pigmentation. It acts as an antioxidant, protecting the skin from oxidative damage, which can cause aging and Glutathione for the Skin Lightening

doi:10.1038/cdd.2009.107 Kavouras JH, Prandovszky E, Valyi-Nagy K, et al

This class of inhibitors has been recently developed, thus there is a scarcity of reported cellular or in vivo data concerning these compounds

Inhibiting LDHA to reduce lactate synthesis, or developing modulators of p300/HDACs to interfere with the dynamic balance of lactylation has the potential to simultaneously disrupt the metabolic dependency and epigenetic remodeling capabilities of tumors, thereby providing new avenues for combination therapies targeting multiple pathways

e4169 (2019)

Together, they address healing from both systemic and localized perspectives