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G6PD deficiency) G6PD deficiency is a common, X-linked reduction in the activity of glucose-6-phosphate dehydrogenase (G6PD), which makes erythrocytes susceptible to oxidative stress and usually causes acute hemolytic anemia in response to a trigger. G6PD enzyme deficiency is the most common enzyme defect

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However, even the least reducing variant roGFP1-iL is still largely oxidized in the ER of human cells and thus hardly capable of detecting oxidative processes in the ER

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