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Many MCAS patients have impaired pathways for converting glutamate into calming GABA, leading to "glutamate excitotoxicity"which can manifest as severe anxiety, insomnia, heart palpitations, and brain fog

Ramos teaches it conceptually as remove, replace, repopulate, repair, and rebalance an honest framing that keeps the work anchored to the underlying driver rather than chasing the symptom

For instance, 95.1% of patients on the 8-week schedule lost fewer than 15 ETDRS letters at week 52

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