glutathione synthetase deficiency blood smear Erythrocytes A rare case of Glutathione
A rare case of Glutathione Synthetase Deficiency in a newborn with normal neurological development on follow up ScienceDirect #imageoftheday, A 24 year old man develops acute jaundice and dark urine after starting trimethoprim sulfamethoxazole. A peripheral smear reveals the specific cellular defects shown. The underlying HEINZ BODIES & BITE CELLS Introduction: Heinz bodies are aggregates of denatured hemoglobin formed after oxidative damage to RBCs. The spleen removes those inclusions, producing bite cells (degmacytes). Classic causes: G6PD Follow Save Share, G6PD deficiency and pyruvate kinase deficiency can look similar in hemolytic anemia questions., The real differentiator is the trigger, pathway, and smear clue., G6PD deficiency = Glutathione Synthetase Deficiency StoryMD
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