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In addition, the oxidants may also originate from cytosolic enzyme systems, e.g., NADPH oxidases, and from exogenous triggers such as ionizing radiation and chemotherapeutics

Figure 3 (C) Heatmap representation of gene expression differences determined by RNA-seq

For instance, airway epithelial cells subjected to CS exhibit marked lipid peroxidation and ferroptotic damage (98)

A broad supplement program does not always guarantee that iron support is adequate in every situation

Some studies have indicated a protective role of estradiol in mitochondria, showing that it can inhibit the passage of ROS into mitochondria as well as preventing mitochondrial collapse and increasing the rate of ATP synthesis (Wang et al., 2003