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469 Secondary Prevention: Newer Evidence Raises Questions Since then, clinical trials have continued to accumulate but have had inconsistent findings

Freezing damages B12, and a frozen vial should be discarded

the mean levels were found to be normal and similar between the intervention and control groups.(11) Only the baseline serum B 12 levels, which were comparable between the treatment and placebo groups, were reported in Farvid et als study.(10) Stracke et al excluded patients with vitamin B 12 deficiency from their study.(13) Vitamin B 12 occurs in several forms known as cobalamins

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