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Overall, activation of these signaling pathways, which are tightly linked to cellular stress responses, promotes the release of pro-inflammatory mediators and cytokines from both airway structural and immune cells, thereby establishing a self-perpetuating inflammatory loop that sustains and aggravates asthma pathology

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Clin Imaging 37(4):631636 Do Van B, Gouel F, Jonneaux A, Timmerman K, Gel P, Ptrault M et al (2016) Ferroptosis, a newly characterized form of cell death in Parkinsons disease that is regulated by PKC