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The same caution applies to other compounds discussed in the context of mitochondrial protection, including matrine, pinocembrin, -lipoic acid, and related pleiotropic agents: although they may improve mitochondrial performance and attenuate ER stress, inflammation, or redox imbalance, they should be regarded primarily as broad stress-response modulators rather than selective regulators of organelle contact sites

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10.1210/jc.2008-2338 82 SharmaV

Tiboni GM, Bucciarelli T, Giampietro F, Sulpizio M, Di Ilio C: Influence of cigarette smoking on vitamin E, vitamin A, beta-carotene and lycopene concentrations in human pre-ovulatory follicular fluid

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