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PLoS One 14:e0223443

Li J, Meng L, Ren S, Jia C, Liu R, Jiang H, Chen J

(Sharma et al., 2016)

Traditional cancer cell models have been extensively used in high-throughput drug screening assays

Arsenic has been proposed to induce cell death through thioredoxin reductase (TrxR) inhibition, with both N-terminal dithiols and C-terminal selenothiol interacting with arsenic compound [54]