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Besides, the regulation of fatty acid metabolism by mitochondria and the formation mechanism of IR in metabolic diseases such as diabetes mellitus and liver diseases are the hot topics of current research [175, 393]

The distance between the edges of the wound were measured at ten different areas from the wound edge to edge using Spot software

Deeply, we demonstrated that DLGAP5 drove inflammasome formation via a dual-axis mechanism, where DLGAP5 initiated NLRP3 inflammasome activation via NF-B pathway, then facilitated inflammasome formation and assembly through enhancing the interaction of NLRP3 and ASC in PYD domain and the binding of ASC and pro-CASPASE-1 in CARD domain, indicating that DLGAP5 acted as a scaffold protein facilitating domain-specific oligomerization

Moreover, there is a lack of structural information for transmission-blocking antibodies in complex with proteins

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