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Chemical resolution Currently, the synthesis of R -ALA on an industrial scale depends on the direct chemical resolution of its racemic mixture, ALA, using R -(+)-methylbenzylamine (RAMBA) as the chiral resolution reagent (Scheme 16)

[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Bandala C., Cortes-Altamirano J.L., Reyes-Long S., Lara-Padilla E., Ilizaliturri-Flores I., Alfaro-Rodrguez A

The gained information has allowed to explain some phenomena observed in toxicological studies performed at the level of cell cultures and of isolated tissue and organ preparations, and to finally propose an explanation for the peculiar toxicological behavior ( i.e

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Drug delivery methods based on nanoparticles have proved to be an effective solution to these problems (Lee et al