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Vitamin B12 Deficiency Symptoms | Signs & NHS Treatment Vitamin B12 deficiency symptoms can be subtle yet far-reaching, affecting the blood, nervous system, and overall wellbeing

For individuals requiring supplementation due to confirmed deficiency or malabsorption, therapeutic doses vary considerably depending on the underlying cause: Dietary deficiency : 50150 micrograms daily orally, or cyanocobalamin tablets as prescribed Pernicious anaemia : Initially hydroxocobalamin 1 mg intramuscularly three times weekly for two weeks, then maintenance injections every two to three months [3] Neurological involvement : More intensive regimens may be required, with hydroxocobalamin injections on alternate days until symptom improvement [3] NICE guidance emphasises that supplementation should be evidence-based rather than speculative

Bariatric surgery can impact the bodys ability to absorb nutrients, so a high supplemental dose of vitamin B12 may be needed to maintain healthy levels.*

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