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No receptor-mediated adverse events (e.g., cardiovascular effects, endocrine disruption) have been reported, consistent with NNMT's limited expression outside metabolic tissues

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The majority of patients at medical clinics seeking peptide therapy for muscle growth are active adults in their 30s, 40s, and 50s who train consistently but have noticed slower recovery, more difficulty maintaining lean mass, and reduced response to the training stimuli that worked well for them a decade earlier