glutathione napqui Mass spectrum and chromatogram of NAPQI–glutathione (GSH) conjugate Most people don't realise this
Most people don't realise this Paracetamol breaks down into a toxic compound called NAPQI. Your liver neutralizes it using glutathione (your body's defense shield). But when you take it too often Acetaminophen NAPQI Hepatotoxicity: A Cell Line Model System Genome Wide Association Study PMC Good ol' paracetamol: 'But an overconsumption takes its toll' Journal of Anaesthesia Practice Acetaminophen induced acute liver injury in mice JC Mossanen, F Tacke, 2015 Alcohol and paracetamol are both processed through the liver. Paracetamol can form a toxic metabolite called NAPQI, which the body usually neutralises safely. But factors like heavy alcohol use, repeated dosing, fasting
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