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DNA binding assay confirms binding of GATA to NBEAL2 enhancer We next performed a DNA binding assay using biotin-labelled DNA fragments that cover the two NBEAL2 enhancer peaks (again referred to as BS-1-2-3 and BS-4-5)

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Qushi Huayu Decoction reduces liver injury in NASH by suppressing the MAPK pathway to protect the colonic tight junction and alters serum lipids by regulating the gut microbiota, including Bacteroides, Blautia, Lachnoclostridium and Turicibacter [157, 158]

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b) the widespread use of antibiotics in animal farming, which impairs B12 production by the animal gut microbiota