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Two plateaus are seen for glycine as it has two ionizable groups (protonated amine and carboxylic acid)

doi: 10.1021/acsami.1c07103 99 PandeyMChoudhuryHD/O Segar SinghSKChetty AnnanNBhattamisraSKGorainBet al

N-acetylcysteine (NAC) suppresses mTOR activation by restoring glutathione levels and exhibits synergistic effects with rapamycin in reducing disease activity [68]

In RLM, certain metabolites (Cit, Pyr and OAA) showed higher levels than in HepM and RHM, possibly due to the lower activity of Krebs cycle enzymes in RLM ( Figure 2 )