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Curcumol enhances cisplatin sensitivity of gastric cancer: involvement of microRNA-7 and the nuclear factor-kappa B/snail family transcriptional repressor 1 axis

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Accordingly, our models predicted a strong induction of several metabolic pathways in non-infected cells of COVID-19 patients based on an increased number of reactions active in the respective context-specific metabolic models, which was even more pronounced in patients with severe disease (Fig

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The wear-and-tear theory posits that prolonged functional stress leads to cellular and tissue degradation, whereas the rate-of-living theory associates higher metabolic rates with reduced lifespan [2,13,15]