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10.1126/science.1259472 117 JiangL.KonN.LiT.WangS

however, persistent or dysregulated activation can drive neurodegeneration through inflammatory signaling, metabolic imbalance and synaptic disruption

Research Administration and Dosing Considerations Published research on BPC-157 in animal models has used various administration routes: Intraperitoneal injection: Common in rodent studies but impractical for veterinary application Subcutaneous injection: More relevant to potential veterinary use Intramuscular injection: Studied in some larger animal models Oral administration: Some research suggests oral bioavailability, though data is limited Topical application: Investigated for wound healing applications Dosing in animal studies varies widely (typically reported as g/kg body weight), and optimal dosing for dogs specifically has not been established through controlled veterinary trials

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