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A phase II randomized clinical trial and mechanistic studies using improved probiotics to prevent oral mucositis induced by concurrent radiotherapy and chemotherapy in nasopharyngeal carcinoma

58,59 Moreover, in 1971, Corey and Skoulos successfully synthesized prostaglandins, and during the 1970s, Brown and Goldstein discovered the low-density lipoprotein receptor pathway, which not only provides cells with the cholesterol necessary for constructing cell membranes and other biomolecules but also helps to maintain cholesterol homeostasis in the plasma

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The group of Gregory Gore described cell death through the mechanism of apoptosis in humans with humans with NASH and successfully introduced the definition of lipotoxicity in patients with NASH [61]