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Moreover, 50 or 100 mg/kg of luteolin has been found to markedly attenuate DSS-induced murine colitis symptoms compared with a DSS group, primarily by inhibiting JNK1/2, phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling, NF-B and STAT3 pathways to exert anti-inflammatory, anti-apoptotic and anti-autophagic effects for colonic homeostasis restoration (68)

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conducted a study involving a smartphone app and sensor (Fitbit) to check the status of the patients during the COVID-19 lockdown, in which they were homebound and social contacts were reduced

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