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It is worth noting that unlicensed medicines can be lawfully supplied in limited circumstances for example, as 'specials' manufactured to meet the specific clinical needs of an individual patient under a prescriber's direction

After several rinses with 0.01 M PBS, the sections were placed in secondary antibody (1:200, Vector Laboratories, Burlingame, CA, USA) at room temperature for 2 h

At this moment several CD38 antibodies are at different phases of clinical testing, with daratumumab already approved for various indications both as monotherapy and in combination with standards of care in MM

N Engl J Med

Others benefit from a slower introduction