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Elevated GH levels subsequently trigger the liver to produce insulin-like growth factor 1 (IGF-1), which mediates many of GH's anabolic effects, including protein synthesis, lipolysis (fat breakdown), and tissue repair

PMC 3316567

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It has also given plenty of scientific support for conditions such as nonalcoholic fatty liver disease, cardiovascular health problems and a host of different applications to neurodegenerative diseases from Alzheimer's Disease to Parkinson's

This permeating effect is secondary to the binding of specific undigestible gliadin fragments to the CXCR3 chemokine receptor with subsequent release of zonulin, a modulator of intercellular tight junctions