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428 In addition, sirt7 deacetylates p53 to inactivate its pro-apoptotic effect, thereby attenuating cardiac hypertrophy and inflammatory cardiomyopathy

Stunning of neutrophils accounts for the anti-inflammatory effects of clodronate liposomes

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Iron overload in cells leads to the accumulation of lipid peroxides, resulting in membrane damage and irreversible organelle damage, thus inducing cell death