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This systematic review evaluates its efficacy and safety in preclinical and clinical studies, focusing on stroke-related outcomes Methods: A systematic search of PubMed, EMBASE, and the Cochrane Library identified studies up to January 2025 examining nerinetides effects on neurological outcomes, infarct size, mortality, and adverse events in ischemic stroke models

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The soy-derived genistein (4,5,7-trihydroxyisoflavone) displays SERM characteristics and represents a promising natural alternative source of biologically active compounds with estrogenic activities

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